A discriminant analysis prediction model of non-syndromic cleft lip with or without cleft palate based on risk factors
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چکیده
منابع مشابه
A discriminant analysis prediction model of non-syndromic cleft lip with or without cleft palate based on risk factors
BACKGROUND A risk prediction model of non-syndromic cleft lip with or without cleft palate (NSCL/P) was established by a discriminant analysis to predict the individual risk of NSCL/P in pregnant women. METHODS A hospital-based case-control study was conducted with 113 cases of NSCL/P and 226 controls without NSCL/P. The cases and the controls were obtained from 52 birth defects' surveillance...
متن کاملEvaluating SKI as a candidate gene for non-syndromic cleft lip with or without cleft palate.
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common of all congenital malformations and has a multifactorial etiology. Findings in mice suggest that the v-ski sarcoma viral oncogene homolog (SKI) gene is a candidate gene for orofacial clefting. In humans, a significant association between rs2843159 within SKI and NSCL/P has been reported in patients from the ...
متن کاملVariation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate.
Non-syndromic cleft lip with or without cleft palate (NSCLP) is a common birth defect. Genetic and environmental factors have been causally implicated and studies have begun to delineate genetic contributions. The Wnt genes are involved in regulating mid-face development and upper lip fusion and are therefore strong candidates for an etiological role in NSCLP. Furthermore, the clf1 region in A/...
متن کاملFOXE1 association with both isolated cleft lip with or without cleft palate, and isolated cleft palate.
Nonsyndromic orofacial clefts are a common complex birth defect caused by genetic and environmental factors and/or their interactions. A previous genome-wide linkage scan discovered a novel locus for cleft lip with or without cleft palate (CL/P) at 9q22-q33. To identify the etiologic gene, we undertook an iterative and complementary fine mapping strategy using family-based CL/P samples from Col...
متن کاملInvestigation of Risk Factors Involved in Cleft Lip and Palate
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ژورنال
عنوان ژورنال: BMC Pregnancy and Childbirth
سال: 2016
ISSN: 1471-2393
DOI: 10.1186/s12884-016-1116-4